estrogenic activity selected plasticizers and potential

estrogenic activity, selected plasticizers and potential

Estrogenic activity, selected plasticizers and potential

Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa J Water Health . 2018 Apr;16(2):253-262. doi: 10.2166/wh.2018.043.

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estrogenic activity, selected plasticizers and potential

Estrogenic activity, selected plasticizers and potential

Estrogenic activity and selected EDCs were found in bottled water samples from South Africa at both temperatures. Bottled water from studies in other countries had varied results. French and Italian bottled waters analyzed using a transcriptional activation assay with HepG2 cells ( Bach et al. 2013 ) and the HELN cell line ( Maggioni et al

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estrogenic activity, selected plasticizers and potential

Estrogenic activity, selected plasticizers and potential

Potential endocrine disrupting chemicals (EDCs) are present in bottled water from various countries. In South Africa (SA), increased bottled water consumption and concomitant increases in plastic packaging create important consequences for public health. This study aimed to screen SA bottled water for estrogenic activity, selected target chemicals and assessing potential health risks. Ten

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estrogenic activity, selected plasticizers and potential

Estrogenic activity, selected plasticizers and potential

This study aimed to screen SA bottled water for estrogenic activity, selected target chemicals and assessing potential health risks. Ten bottled water brands were exposed to 20 °C and 40 °C over 10 days. Estrogenic activity was assessed using the recombinant yeast estrogen screen (YES) and the T47D-KBluc reporter gene assay.

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effects of plasticizers and their mixtures on estrogen

Effects of plasticizers and their mixtures on estrogen

The estrogenic activities of the compounds were assessed in MVLN cells, stably transfected with an estrogen receptor (ER) luciferase reporter vector. Furthermore, the combined effect of a multi-components mixture of six plasticizers was evaluated for its estrogenic and TH-like activities.

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most plastic products release estrogenic chemicals: a

Most Plastic Products Release Estrogenic Chemicals: A

Background: Chemicals having estrogenic activity (EA) reportedly cause many adverse health effects, especially at low (picomolar to nanomolar) doses in fetal and juvenile mammals.Objectives: We sought to determine whether commercially available plastic resins and products, including baby bottles and other products advertised as bisphenol A (BPA) free, release chemicals having EA.Methods: We

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comparative toxicity, oxidative stress and endocrine

Comparative toxicity, oxidative stress and endocrine

Some phthalates, such as BBP, DBP and DEHP, may bind to the estrogen receptor and have a weak estrogenic activity, enhancing the proliferation of MCF-7 cells (Harris et al., 1997, Okubo et al., 2003), while such estrogenic effects was not detect in-vivo (Milligan et al., 1998). Moreover, exposure to plasticizers leads to the activation of

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[pdf] endocrine disruptors in bottled mineral water: total

[PDF] Endocrine disruptors in bottled mineral water: total

Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa. N. Aneck-Hahn , M. V. Van Zijl , +4 authors C. Jager Chemistry, Medicine

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most plastic products release estrogenic chemicals: a

Most Plastic Products Release Estrogenic Chemicals: A

Background: Chemicals having estrogenic activity (EA) reportedly cause many adverse health effects, especially at low (picomolar to nanomolar) doses in fetal and juvenile mammals.Objectives: We sought to determine whether commercially available plastic resins and products, including baby bottles and other products advertised as bisphenol A (BPA) free, release chemicals having EA.Methods: We

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comparison of in vitro endocrine activity of phthalates and

Comparison of In Vitro Endocrine Activity of Phthalates and

Regarding the 2 other alternative plasticizers DEHT and TOTM, neither of them exhibited any estrogenic or antiestrogenic activity in the E-Screen assay or any androgenic or antiandrogenic activity in the AR gene reporter assay in MDA-kb2 cells.

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potential endocrine disrupting properties of toys for babies

Potential endocrine disrupting properties of toys for babies

Plastic toys mouthed by children may be a source of exposure to endocrine active substances. The purpose of this study was to measure hormonal activity of substances leaching from toys and to identify potential endocrine disruptors causing that activity. For this purpose, migration experiments of toys were conducted in saliva simulants. The CALUX® assays were used to detect (anti-) estrogenic

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toxicity and estrogenic endocrine disrupting activity of

Toxicity and Estrogenic Endocrine Disrupting Activity of

Phthalates, widely used in flexible plastics and consumer products, have become ubiquitous contaminants worldwide. This study evaluated the acute toxicity and estrogenic endocrine disrupting activity of butyl benzyl phthalate (BBP), di(n-butyl) phthalate (DBP), bis(2-ethylhexyl) phthalate (DEHP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP), di-n-octyl phthalate (DNOP) and their

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estrogenic and androgenic potential of phthalates and their

Estrogenic and Androgenic Potential of Phthalates and Their

ER recombinant gene assay in yeast Estrogenic activity Yes 36 ER binding assay in human MCF-7 cell LOEC, estrogenic activity 10-6 ~10-5 M28 hERα binding assay IC50, estrogenic activity 27.5×10-6 M29

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estrogenic activity of capsule coffee using the vm7luc4e2

Estrogenic activity of capsule coffee using the VM7Luc4E2

DMTP was not found to possess estrogenic potential in similar reporter gene assays, although did demonstrate estrogen receptor agonist activity in a cell proliferation assay (Peng et al., 2019). To our knowledge, the estrogenic potential of BP and DBP have not yet been tested using the VM7Luc4E2 assay.

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distribution and estrogenic potential of endocrine disrupting

Distribution and estrogenic potential of endocrine disrupting

The estrogenic activity interference encompasses interference effects on reproduction and growth of the organisms, disorders on the endocrine system and nervous system, and abnormality on immune function (Campbell et al., 2006; Crisp et al., 1998).

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[pdf] endocrine disruptors in bottled mineral water: total

[PDF] Endocrine disruptors in bottled mineral water: total

Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa. N. Aneck-Hahn , M. V. Van Zijl , +4 authors C. Jager Chemistry, Medicine

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potential endocrine disrupting properties of toys for babies

Potential endocrine disrupting properties of toys for babies

Plastic toys mouthed by children may be a source of exposure to endocrine active substances. The purpose of this study was to measure hormonal activity of substances leaching from toys and to identify potential endocrine disruptors causing that activity. For this purpose, migration experiments of toys were conducted in saliva simulants. The CALUX® assays were used to detect (anti-) estrogenic

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examination of the estrogenicity of 2,4,6,2',6

Examination of the estrogenicity of 2,4,6,2',6

These studies demonstrate that in addition to the hydroxylated metabolites, selected parent PCB congeners may also exhibit estrogenic and antiestrogenic activities. Full text Get a printable copy (PDF file) of the complete article (4.3M), or click on a page image below to browse page by page.

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distribution and estrogenic potential of endocrine disrupting

Distribution and estrogenic potential of endocrine disrupting

The estrogenic activity interference encompasses interference effects on reproduction and growth of the organisms, disorders on the endocrine system and nervous system, and abnormality on immune function (Campbell et al., 2006; Crisp et al., 1998).

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toxicity and estrogenic endocrine disrupting activity of

Toxicity and Estrogenic Endocrine Disrupting Activity of

For both estrogenic activity and enhanced-/anti-estrogenic activity pre-testing, about eight ChgH-EGFP transgenic medaka (O. melastigma) eleutheroembryos were exposed to each concentration of phthalate or phthalate mixture for 24 hrs and these were then observed under a stereomicroscope (Leica MZ10F) equipped with a UV excitation light source

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estrogen-like activity of seafood related to environmental

Estrogen-like activity of seafood related to environmental

Estrogenic activity of organic extracts of seafood (200 g wet weight) and standard PCBs was tested by S. cerevisiae yeast strain (RMY326 ER-ERE) containing the human estrogen receptor (hERa) and a Xenopus laevis vitellogenin estrogen-responsive element (ERE) linked to a reporter gene lac Z encoding for the enzyme β-galactosidase.

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determination of in vivo estrogenic potential of di-isobutyl

Determination of in vivo estrogenic potential of Di-isobutyl

Estrogenic potential of Di-isobutyl phthalate (DIBP) and Di-isononyl phthalate (DINP) was studied using two different test systems. Two different doses of DIBP (250 and 1250 mg/kg) and DINP (276 and 1380 mg/kg) were administered to immature female rats (20 days old) orally once daily for 3 and 20 days in uterotrophic and pubertal assay, respectively. The animals were sacrificed on day 4 and

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(pdf) estrogenic and androgenic potential of phthalates and

(PDF) Estrogenic and Androgenic Potential of Phthalates and

Anti-estrogen assay in human MCF-7 cell Anti-estrogenic activity Y es hERα transactivation assay in CHO cells REC , estrogenic activity 1.7×10 M3 2 hERβ transactivation assay in CHO cells REC

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potential estrogenic effects of wastewaters on gene

Potential estrogenic effects of wastewaters on gene

Fortunately, the effects that estrogenic contaminants have on resident aquatic biota and natural ecosystems can be evaluated effectively, because methods that quantify estrogen activity and very low concentrations of hormones and nonhormone EDCs have advanced over the last 20 yr. E-screen assay methods 23, 24 are now commonly used to quantify

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